Publications

Selected publications (2016 -2021)

Modeling, optimization, and comparable efficacy of T cell and hematopoietic stem cell gene editing for treating hyper-IgM syndrome

Valentina Vavassori, Elisabetta Mercuri, Genni E Marcovecchio, Maria C Castiello, Giulia Schiroli, Luisa Albano, Carrie Margulies, Frank Buquicchio, Elena Fontana, Stefano Beretta , Ivan Merelli, Andrea Cappelleri, Paola Rancoita, Vassilios Lougaris, Alessandro Plebani, Maria Kanariou, Arjan Lankester, Francesca Ferrua, Eugenio Scanziani, Cecilia Cotta-Ramusino, Anna Villa, Luigi Naldini*, Pietro Genovese*

EMBO Molecular Medicine 2021

Efficient gene editing of human long-term hematopoietic stem cells validated by clonal tracking

Samuele Ferrari*, Aurelien Jacob*, Stefano Beretta, Giulia Unali, Luisa Albano, Valentina Vavassori, Davide Cittaro, Dejan Lazarevic, Chiara Brombin, Federica Cugnata, Anna Kajaste-Rudnitski, Ivan Merelli, Pietro Genovese* & Luigi Naldini*

Nature Biotechnology 2020

Precise Gene Editing Preserves Hematopoietic Stem Cell Function following Transient p53-Mediated DNA Damage Response

Giulia Schiroli*, Anastasia Conti*, Samuele Ferrari, Lucrezia Della Volpe, Aurelien Jacob, Luisa Albano, Stefano Beretta, Andrea Calabria, Valentina Vavassori, Patrizia Gasparini, Eralda Salataj, Delphine Ndiaye-Lobry, Chiara Brombin, Julie Chaumeil, Eugenio Montini, Ivan Merelli, Pietro Genovese*, Luigi Naldini*, Raffaella Di Micco*

Cell Stem Cell 2019

Phagocytosis-shielded lentiviral vectors improve liver gene therapy in nonhuman primates

Michela Milani, Andrea Annoni, Federica Moalli, Tongyao Liu, Daniela Cesana, Andrea Calabria, Sara Bartolaccini, Mauro Biffi, Fabio Russo, Ilaria Visigalli, Andrea Raimondi, Susannah Patarroyo-White, Douglas Drager, Patrizia Cristofori, Eduard Ayuso 6, Eugenio Montini, Robert Peters, Matteo Iannacone, Alessio Cantore*, Luigi Naldini*

Science Translational Medicine 2019

EVIR: chimeric receptors that enhance dendritic cell cross-dressing with tumor antigens

Mario Leonardo Squadrito, Chiara Cianciaruso, Sarah K Hansen, Michele De Palma

Nature Methods 2018

Interferon gene therapy reprograms the leukemia microenvironment inducing protective immunity to multiple tumor antigens

Giulia Escobar, Luigi Barbarossa, Giulia Barbiera, Margherita Norelli, Marco Genua, Anna Ranghetti, Tiziana Plati, Barbara Camisa, Chiara Brombin, Davide Cittaro, Andrea Annoni, Attilio Bondanza, Renato Ostuni, Bernhard Gentner*, Luigi Naldini*

Nature Communications 2018

Suppression of microRNA activity amplifies IFN-γ-induced macrophage activation and promotes anti-tumour immunity

Caroline Baer*, Mario Leonardo Squadrito*, Damya Laoui, Danielle Thompson, Sarah K Hansen, Anna Kiialainen, Sabine Hoves, Carola H Ries, Chia-Huey Ooi, Michele De Palma

Nature Cell Biology 2016

miRNA-126 Orchestrates an Oncogenic Program in B Cell Precursor Acute Lymphoblastic Leukemia

Silvia Nucera, Alice Giustacchini, Francesco Boccalatte, Andrea Calabria, Cristiana Fanciullo, Tiziana Plati, Anna Ranghetti, Jose Garcia-Manteiga, Davide Cittaro, Fabrizio Benedicenti, Eric R Lechman, John E Dick, Maurilio Ponzoni, Fabio Ciceri, Eugenio Montini, Bernhard Gentner*, Luigi Naldini*

Cancer Cell 2016

Inheritable Silencing of Endogenous Genes by Hit-and-Run Targeted Epigenetic Editing

Angelo Amabile*, Alessandro Migliara*, Paola Capasso, Mauro Biffi, Davide Cittaro, Luigi Naldini*, Angelo Lombardo*

Cell 2016

www.cancerbiotechnology.com – Thanks for visiting our website!