Cancer Biotechnology

Science, Innovation, Curiosity

Leveraging gene tools to design new therapeutic interventions



We are employing vectors to genetically engineer cancer and immune cells to explore new therapeutic interventions and unravel new biological insights.

our group


We are a group of scientists and students with academic formation in biomedical sciences. Ours is not another job, but a responsibility.  A big one. 

Our lab

About us

Our team is part of the Unit of Prof. Luigi Naldini, director of the San Raffaele Telethon Institute for Gene Therapy, located at the IRCCS San Raffaele, in Italy, Milan.

Selected Publications

Laboratory-Scale Lentiviral Vector Production and Purification for Enhanced Ex Vivo and In Vivo Genetic Engineering.

Soldi M, Sergi Sergi L, Unali G, Kerzel T, Cuccovillo I, Capasso P, Annoni A, Biffi M, Rancoita PMV, Cantore A, Lombardo A, Naldini L, Squadrito ML*, Kajaste-Rudnitski A*.

A.Mol Ther Methods Clin Dev. 2020 Oct 20;19:411-425.

EVIR: chimeric receptors that enhance dendritic cell cross-dressing with tumor antigens.

Squadrito ML, Cianciaruso C, Hansen SK, De Palma M.
Nat Methods. 2018 Mar;15(3):183-186. 


We acknowledge Fondazione CARIPLO and FRRB for supporting our Research. – Thanks for visiting our website!